The molecular pathology guidelines have been revised:
- To clarify nucleic acid refers to both DNA and RNA
- To define copy number variants and link them to Dup/Del analysis
Septin9 (SEPT9) blood testing has its own code in 2017 – CPT 81327.
The genomic sequencing procedures (GSP) subsection guidelines were revised to clarify that reporting a GSP includes genes that are listed in more than one code descriptor.
Code 81422 was established for reporting a GSP for fetal chromosomal microdeletions.
Code 81539 was established for reporting a multianalyte assay with algorithmic analyses (MAAA) test that measures risk of high-grade, aggressive prostate cancer. This replaces the deleted administrative code 0010M.